Section: New Results

Computational Toxicology

Participant :

It is now well recognized that toxicology has entered a new era. Previously mainly based on animal testing, toxicology is now turning to in vitro and in silico experiments. To assess the risk of chemicals but also to gather and to interpret the massive amounts of experimental data generated by modern toxicology, the development of mathematical and computational tools are essential. An important element in risk assessment of chemicals is the human bioaccumulative potential. We developed a predictive tool for human bioaccumulation assesment using a physiologically based toxicokinetic model [53] .